Details

Autor(en) / Beteiligte

• Gómez-Ramos, M.M.
• Ferrer, C.
• Malato, O.
• Agüera, A.
• Fernández-Alba, A.R.

Titel

Liquid chromatography-high-resolution mass spectrometry for pesticide residue analysis in fruit and vegetables: Screening and quantitative studies

Ist Teil von

• Journal of Chromatography A, 2013-04, Vol.1287, p.24-37

Ort / Verlag

Amsterdam: Elsevier B.V

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• ► The work reviews LC-HRMS for the analysis of pesticides in fruit and vegetables. ► Discuss capabilities of HRMS to identify, confirm and quantify pesticides. ► HRMS is as a reliable technology for the analysis of pesticides in food. ► Main drawbacks are due to software shortcomings and lack of optimization parameters. This work reviews the current state-of-the-art of liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) techniques applied to the analysis of pesticides in fruit-based and vegetable-based matrices. Nowadays, simultaneous trace analysis of hundreds of pesticides from different classes is required, preferably in just one run. The most commonly used QqQ-MS technology presents certain limitations in its application in a cost and effective way when analyzing a large number of pesticides. Thus, this review includes HRMS technology as a reliable complementary alternative allowing the analysis of a wide range of pesticides in food. Its capabilities and limitations in identifying, confirming and quantifying pesticides are discussed. HRMS instruments can adequately address such issues; however, the main drawbacks are as a result of insufficient prior optimization of the operational parameters during non-target analysis in full-scan mode and due to software shortcomings.