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Facile synthesis and in vitro bioactivity of monodispersed mesoporous bioactive glass sub-micron spheres
Ist Teil von
Materials letters, 2013-09, Vol.106, p.452-455
Ort / Verlag
Elsevier B.V
Erscheinungsjahr
2013
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
This paper reports a facile method for fabricating monodispersed mesoporous bioactive glass sub-micron spheres (MBGS) using dodecylamine (DDA) as a catalyst and template agent in sol–gel process. The morphology, structure and in vitro bioactivity of MBGS were investigated by various methods. The results indicate that using DDA as the structure directing agent and hydrolysis catalyst is in favor of preparing the MBGS with mesoporous surface structure, large specific surface area (362.073m2g−1), relatively homogeneous particle size (~560nm) and good apatite-forming activity. The unique structure and properties may turn MBGS into a good candidate as a drug delivery carrier or an injectable biomaterial for bone tissue regeneration.
•Monodispersed mesoporous bioactive glass sub-micron spheres (MBGS) were successfully synthetized by using dodecylamine (DDA) as a catalyst and template agent in sol–gel process.•The novel MBGS show larger specific surface area (362.073m2g−1), relatively homogeneous particle size (∼560nm) and good apatite-forming activity.•The unique structure and properties may turn MBGS into a good candidate as a drug delivery carrier or an injectable biomaterial for bone tissue regeneration.