Neuroscience, 2014-09, Vol.277, p.885-901
2014
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats
- Ist Teil von
- Neuroscience, 2014-09, Vol.277, p.885-901
- Ort / Verlag
- United States: Elsevier Ltd
- Erscheinungsjahr
- 2014
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Neonatal antibiotic treatment leads to an increase in visceral sensitivity in adulthood in rats. • Visceral hypersensitivity develops in the absence of changes in other behavioral or overt physiological responses. • Different antibiotic treatments in early-life lead to specific changes in targets of pain in the spinal cord.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0306-4522eISSN: 1873-7544DOI: 10.1016/j.neuroscience.2014.07.054Titel-ID: cdi_proquest_miscellaneous_1639985133
- Format
- –
- Schlagworte
- Animals, Animals, Newborn, Anti-Bacterial Agents - pharmacology, antibiotic, Anxiety - physiopathology, Bacitracin - pharmacology, behavior, Behavior, Animal - physiology, brain–gut axis, Cognition - physiology, Female, Gastrointestinal Tract - drug effects, Gastrointestinal Tract - microbiology, Hyperalgesia - physiopathology, Male, microbiota, Microbiota - drug effects, Microbiota - physiology, Natamycin - pharmacology, Neomycin - pharmacology, neonatal, Neurology, Rats, Sprague-Dawley, Vancomycin - pharmacology, visceral pain, Visceral Pain - physiopathology