Details

Autor(en) / Beteiligte

• Malik, Rehan
• Aneni, Ehimen C
• Roberson, Lara
• Ogunmoroti, Oluseye
• Ali, Shozab S
• Shaharyar, Sameer
• Younus, Adnan
• Jamal, Omar
• Aziz, Muhammad A
• Martin, Seth S
• Blaha, Michael J
• Feldman, Theodore
• Agatston, Arthur S
• Veledar, Emir
• Nasir, Khurram

Titel

Measuring coronary artery calcification: Is serum vitamin D relevant?

Ist Teil von

• Atherosclerosis, 2014-12, Vol.237 (2), p.734-738

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

2014

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Objectives : To synthesize evidence of the association between low vitamin D levels and subclinical coronary atherosclerosis measured by coronary artery calcium (CAC). Methods : A systematic MEDLINE search was conducted for relevant published literature. Ten studies (7 cross-sectional, 3 longitudinal) met the inclusion criteria. Results : Three of 6 studies showed association with CAC prevalence (CAC >0 or >10). Four of 8 studies found an association with CAC severity. One of two studies reported an association with CAC progression, while the only study that assessed CAC incidence did not find a significant relationship. Several of the studies had small sample sizes, many did not adjust for confounders and the cut-off for low vitamin D was inconsistent. Conclusion : There is insufficient evidence to support a consistent association between low vitamin D levels and CAC. Further high-quality studies are needed to examine serum 25-OH vitamin D in relation to subclinical coronary atherosclerosis.