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The prevalence of Parkinson's disease: A systematic review and meta-analysis
Movement disorders, 2014-11, Vol.29 (13), p.1583-1590
Pringsheim, Tamara
Jette, Nathalie
Frolkis, Alexandra
Steeves, Thomas D.L.
2014
Details
Autor(en) / Beteiligte
Pringsheim, Tamara
Jette, Nathalie
Frolkis, Alexandra
Steeves, Thomas D.L.
Titel
The prevalence of Parkinson's disease: A systematic review and meta-analysis
Ist Teil von
Movement disorders, 2014-11, Vol.29 (13), p.1583-1590
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2014
Link zum Volltext
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
Parkinson's Disease (PD) is a common neurodegenerative disorder. We sought to synthesize studies on the prevalence of PD to obtain an overall view of how the prevalence of this disease varies by age, by sex, and by geographic location. We searched MEDLINE and EMBASE for epidemiological studies of PD from 1985 to 2010. Data were analyzed by age group, geographic location, and sex. Geographic location was stratified by the following groups: 1) Asia, 2) Africa, 3) South America, and 4) Europe/North America/Australia. Meta‐regression was used to determine whether a significant difference was present between groups. Forty‐seven studies were included in the analysis. Meta‐analysis of the worldwide data showed a rising prevalence of PD with age (all per 100,000): 41 in 40 to 49 years; 107 in 50 to 59 years; 173 in 55 to 64 years; 428 in 60 to 69 years; 425 in 65 to 74 years; 1087 in 70 to 79 years; and 1903 in older than age 80. A significant difference was seen in prevalence by geographic location only for individuals 70 to 79 years old, with a prevalence of 1,601 in individuals from North America, Europe, and Australia, compared with 646 in individuals from Asia (P < 0.05). A significant difference in prevalence by sex was found only for individuals 50 to 59 years old, with a prevalence of 41 in females and 134 in males (P < 0.05). PD prevalence increases steadily with age. Some differences in prevalence by geographic location and sex can be detected. © 2014 International Parkinson and Movement Disorder Society
Sprache
Englisch
Identifikatoren
ISSN: 0885-3185
eISSN: 1531-8257
DOI: 10.1002/mds.25945
Titel-ID: cdi_proquest_miscellaneous_1627984215
Format
–
Schlagworte
Humans
,
Movement disorders
,
Parkinson Disease - epidemiology
,
Parkinson's disease/Parkinsonism
,
prevalence studies
,
risk factors in epidemiology
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