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Insights into Pediatric Herpes Simplex Encephalitis From a Cohort of 21 Children From the California Encephalitis Project, 1998–2011
Ist Teil von
The Pediatric infectious disease journal, 2014-12, Vol.33 (12), p.1287-1288
Ort / Verlag
Hagerstown, MD: by Lippincott Williams & Wilkins, Inc
Erscheinungsjahr
2014
Quelle
MEDLINE
Beschreibungen/Notizen
Twenty-one children with confirmed herpes simplex encephalitis were identified in the California Encephalitis Project. Noteworthy features included 6 (29%) patients with an initial negative herpes simplex virus cerebrospinal fluid polymerase chain reaction test and 13 (59%) patients with extratemporal lobe involvement identified by neuroimaging. Eleven cases were <4 years of age, but all 4 fatal cases occurred in adolescents.