Details

Autor(en) / Beteiligte

• Tuncal, Akile
• Aydin, Hikmet Hakan
• Askar, Niyazi
• Ozkaya, Ali Burak
• Ergenoglu, Ahmet Mete
• Yeniel, Ahmet Ozgur
• Akdemir, Ali
• Ak, Handan

Titel

Increased expression of electron transport chain genes in uterine leiomyoma

Ist Teil von

• Annals of clinical and laboratory science, 2014, Vol.44 (4), p.466-468

Ort / Verlag

United States

Erscheinungsjahr

2014

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• The etiology and pathophysiology of uterine leiomyomas, benign smooth muscle tumors of the uterus, are not well understood. To evaluate the role of mitochondria in uterine leiomyoma, we compared electron transport gene expressions of uterine leiomyoma tissue with myometrium tissue in six uterine leiomyoma patients by RT-PCR array. Our results showed an average of 1.562 (±0.445) fold increase in nuclear-encoded electron transport genes. These results might suggest an increase in size, number, or activity of mitochondria in uterine leiomyoma that, to our knowledge, has not been previously reported.