Details

Autor(en) / Beteiligte

• Schaumburg, F.
• Idelevich, E.A.
• Peters, G.
• Mellmann, A.
• von Eiff, C.
• Becker, K.

Titel

Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004–2011)

Ist Teil von

• Clinical microbiology and infection, 2014-09, Vol.20 (9), p.O554-O557

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004–2005 and 2010–2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim–sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes 003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.