Chemosphere (Oxford), 1991, Vol.23 (11), p.1925-1931
1991
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Inductive potency of TCDD, TBDD and three 2,3,7,8-mixed-halogenated dioxins in liver microsomes of male rats. Enzyme kinetic considerations
- Ist Teil von
- Chemosphere (Oxford), 1991, Vol.23 (11), p.1925-1931
- Ort / Verlag
- Oxford: Elsevier Ltd
- Erscheinungsjahr
- 1991
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- The enzyme inducing potency of single doses of three 2,3,7,8-substituted mixed halogenated dibenzo- p-dioxins was investigated and compared with 2,3,7,8-TCDD and 2,3,7,8-TBDD. All substances showed a quite similar potency for EROD induction. The use of a substrate concentration of 0.5 μM ethoxyresorufin is strongly recommended.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0045-6535eISSN: 1879-1298DOI: 10.1016/0045-6535(91)90040-KTitel-ID: cdi_proquest_miscellaneous_16155577
- Format
- –
- Schlagworte
- 2,3,7,8-Tetrabromodibenzo- p-dioxin, 2,3,7,8-Tetrachlorodibenzo- p-dioxin, 2,3,7-Tribromo-8-chlorodibenzo- p-dioxin, 2,3-Dibromo-7,8-dichlorodibenzo- p-dioxin, 2-Bromo-3,7,8-trichlorodibenzo- p-dioxin, Biological and medical sciences, Chemical and industrial products toxicology. Toxic occupational diseases, Enzyme induction, Ethoxyresorufin O-deethylase, Wistar rats, Medical sciences, Toxicology, Various organic compounds