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Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear
Ist Teil von
Food chemistry, 2015-03, Vol.171, p.251-257
Ort / Verlag
England: Elsevier Ltd
Erscheinungsjahr
2015
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
•Five novel polycyclic prenylated phenols were isolated from G. cochlear.•Compounds 1–5 were a series of enantiomers.•Compounds 1–8 showed significant antioxidant activities.
Seven new prenylated phenols, five novel phenols (1–5) with polycyclic skeleton and two new phenols (6 and 7) with a carbon chain, along with one known compound (8) were isolated from the fruiting bodies of Ganoderma cochlear. The structures of new compounds were elucidated by the spectroscopic technologies, X-ray crystallography analysis and chiral HPLC chromatography. All compounds showed antioxidant effect in radical scavenging assays and a plausible biosynthetic pathway for 1–8 was proposed.