Details

Autor(en) / Beteiligte

• ACKERMANN-LIEBRICH, U
• LEUENBERGER, P
• GRIZE, L
• KARRER, W
• KELLER, R
• KELLER-WOSSIDLO, H
• KÜNZLI, N
• MARTIN, B. W
• MEDICI, T. C
• PERRUCHOUD, A. P
• SCHÖNI, M. H
• TSCHOPP, J. M
• SCWARTZ, J
• VILLIGER, B
• WÜTHRICH, B
• ZELLWEGER, J. P
• ZEMP, E
• SCHINDLER, C
• MONN, C
• BOLOGNINI, G
• BONGARD, J. P
• BRÄNDLI, O
• DOMENIGHETTI, G
• ELSASSER, S

Titel

Lung function and long term exposure to air pollutants in Switzerland

Ist Teil von

• American journal of respiratory and critical care medicine, 1997, Vol.155 (1), p.122-129

Ort / Verlag

New York, NY: American Lung Association

Erscheinungsjahr

1997

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The effect of long-term exposure to air pollutants was studied in a cross-sectional population-based sample of adults (aged 18 to 60 yr; n = 9,651) residing in eight different areas in Switzerland. Standardized medical examination included questionnaire data, lung function tests, skin-prick testing, and end-expiratory CO concentration. The impact of annual means of air pollutants on FVC and FEV sub(1) was tested (controlling for age and age squared, sex, height, weight, educational level, nationality, and workplace exposure). Analyses were done separately for healthy never-smokers, ex-smokers (controlling for pack-yr), for current smokers (controlling for cigarettes per day and pack-yr smoked), and for the whole population. Significant and consistent effects on FVC and FEV sub(1) were found for NO sub(2), SO sub(2), and particular matter < 10 mu m (PM sub(10)) in all subgroups and in the total population, with PM sub(10) showing the most consistent effect of a 3.4% change in FVC per 10 mu g/m super(3). Results for ozone were less consistent. Atopy did not influence this relationship. The limited number of study areas and high inter-correlation between the pollutants make it difficult to assess the effect of one single pollutant. Our conclusion is that air pollution from fossil fuel combustion, which is the main source of air pollution with SO sub(2), NO sub(2), and PM sub(10) in Switzerland, is associated with decrements in lung function parameters in this study.