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Language impairment in cerebellar ataxia
Movement disorders, 2014-09, Vol.29 (10), p.1307-1312
van Gaalen, Judith
de Swart, Bert J.M.
Oostveen, Judith
Knuijt, Simone
van de Warrenburg, Bart P.C.
Kremer, Berry (H.) P.H
2014
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
van Gaalen, Judith
de Swart, Bert J.M.
Oostveen, Judith
Knuijt, Simone
van de Warrenburg, Bart P.C.
Kremer, Berry (H.) P.H
Titel
Language impairment in cerebellar ataxia
Ist Teil von
Movement disorders, 2014-09, Vol.29 (10), p.1307-1312
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2014
Quelle
Wiley HSS Collection
Beschreibungen/Notizen
ABSTRACT Background Several studies have suggested that language impairment can be observed in patients with cerebellar pathology. The aim of this study was to investigate language performance in patients with spinocerebellar ataxia type 6 (SCA6). Methods We assessed speech and language in 29 SCA6 patients with standardized linquistic tests and correlated this with the severity of ataxia, as quantified by the Scale of Assessment and Rating of Ataxia. Results Individual patients show mild‐to‐moderate linguistic impairment. Linguistic abnormalities were most distinct on the writing and comprehension subtests. A strong correlation between severity of ataxia and linguistic performance was consistently found. Conclusions This study confirms the occurrence of linguistic impairments in patients with cerebellar degenerative diseases, such as SCA6. The relation between linguistic abnormalities and severity of ataxia provides further evidence for a role of the cerebellum in linguistic processing. © 2014 International Parkinson and Movement Disorder Society
Sprache
Englisch
Identifikatoren
ISSN: 0885-3185
eISSN: 1531-8257
DOI: 10.1002/mds.25854
Titel-ID: cdi_proquest_miscellaneous_1561972598
Format
–
Schlagworte
Aged
,
Aged, 80 and over
,
aphasia
,
Calcium Channels - genetics
,
cerebellar ataxia
,
Cerebellar Ataxia - complications
,
Cognition Disorders - diagnosis
,
Cognition Disorders - etiology
,
Female
,
Humans
,
Language Disorders - diagnosis
,
Language Disorders - etiology
,
language impairment
,
Male
,
Middle Aged
,
Movement disorders
,
Neuropsychological Tests
,
Severity of Illness Index
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