Details

Autor(en) / Beteiligte

• Lee, Cheol Whan
• Ahn, Jung-Min
• Lee, Jong-Young
• Kim, Won-Jang
• Park, Duk-Woo
• Kang, Soo-Jin
• Lee, Seung-Whan
• Kim, Young-Hak
• Park, Seong-Wook
• Park, Seung-Jung

Titel

Long-term (8 year) outcomes and predictors of major adverse cardiac events after full metal jacket drug-eluting stent implantation

Ist Teil von

• Catheterization and cardiovascular interventions, 2014-09, Vol.84 (3), p.361-365

Ort / Verlag

United States: Blackwell Publishing Ltd

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Objectives We examined long‐term outcomes and predictors of major adverse cardiac events after the full metal jacket (FMJ) stent implantation. Background The FMJ procedure has been used to treat diffuse coronary artery disease (CAD), but long‐term outcomes remain unknown. Methods The study population consisted of 347 consecutive patients (352 lesions) who had been treated for de novo diffuse CAD with FMJ stents (stent length ≥ 60 mm). Results The mean age was 61.0 ± 10.1 years, and the stent length was 71.9 ± 13.7 mm. The procedural success rate was 97.7%. Major in‐hospital complications (one death and two acute stent thromboses) occurred in three patients (0.7%). The median follow‐up was 101 months (interquartile range, 95–108 months). During follow‐up, there were 60 deaths (33 cardiac), 20 myocardial infarctions, and 94 revascularizations. Definite stent thrombosis occurred in 12 patients. The event‐free survival rate for cardiac death, cardiac death/myocardial infarction, or cardiac death/myocardial infarction/target lesion revascularization was 90.5 ± 1.6, 85.8 ± 1.9, and 71.6 ± 2.5% at 8 years, respectively. Left ventricular dysfunction (ejection fraction < 45%) was an independent predictor of cardiac death (OR: 4.88; 95% CI: 1.81–13.13; P = 0.002). Left ventricular dysfunction and a stent length > 80 mm were significantly related to cardiac death/myocardial infarction. Likewise, a stent length > 80 mm was an independent predictor of cardiac death/myocardial infarction/target lesion revascularization (OR: 2.45; 95% CI: 1.16–5.19; P = 0.019). Conclusion Long‐term outcomes appear favorable after FMJ procedures, and left ventricular dysfunction and a stent length > 80 mm are major predictors of major adverse cardiac events. These findings might be useful in identifying the most suitable treatments for patients with very diffuse CAD. © 2013 Wiley Periodicals, Inc.