Nature genetics, 2014-05, Vol.46 (5), p.421-422
2014
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Details
- Autor(en) / Beteiligte
- Titel
- ACVR1 mutations and the genomic landscape of pediatric diffuse glioma
- Ist Teil von
- Nature genetics, 2014-05, Vol.46 (5), p.421-422
- Ort / Verlag
- New York: Nature Publishing Group US
- Erscheinungsjahr
- 2014
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Pediatric diffuse gliomas are rare but aggressive brain tumors for which effective therapies are unavailable. New studies identify recurrent mutations of the ACVR1 gene in these tumors, identify molecular subtypes and highlight differences between gliomas affecting children and adults.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1061-4036eISSN: 1546-1718DOI: 10.1038/ng.2970Titel-ID: cdi_proquest_miscellaneous_1554954136
- Format
- –
- Schlagworte
- 692/699/67/1922, Activin Receptors, Type I - genetics, Agriculture, Animal Genetics and Genomics, Animals, Astrocytoma - genetics, Biomedicine, Brain Neoplasms - genetics, Brain Stem Neoplasms - genetics, Cancer Research, Families & family life, Gene Expression Regulation, Neoplastic - genetics, Gene Function, Gene mutations, Genes, Genetic aspects, Genetic research, Genome, Human - genetics, Genomes, Genomics, Glioma - genetics, Gliomas, Health aspects, Human Genetics, Humans, Kinases, Mutation, Mutation - genetics, Mutation, Missense - genetics, news-and-views, Pediatrics, Phosphorylation, Signal Transduction - genetics, Studies, Tumors, Tumors in children