Internal Medicine, 2014, Vol.53(16), pp.1809-1812
2014
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- Autor(en) / Beteiligte
- Titel
- Diffuse Parenchymal Pulmonary Amyloidosis Showing an Objective Response to Bortezomib-based Chemotherapy
- Ist Teil von
- Internal Medicine, 2014, Vol.53(16), pp.1809-1812
- Ort / Verlag
- Japan: The Japanese Society of Internal Medicine
- Erscheinungsjahr
- 2014
- Quelle
- EZB-FREE-00999 freely available EZB journals
- Beschreibungen/Notizen
- A 77-year-old woman was admitted because of bilateral hand numbness and dyspnea on exertion. Her serum IgG was increased, and a bone marrow aspiration analysis supported a diagnosis of multiple myeloma. Additionally, computed tomography scans of the chest showed bilateral ground glass attenuations, linear opacities, and consolidations. Transbronchial lung biopsy revealed Congo Red-positive amorphous eosinophilic deposits. She was therefore diagnosed with diffuse parenchymal pulmonary amyloidosis accompanied by multiple myeloma. Following combination chemotherapy including bortezomib, her serum monoclonal protein levels were normalized, and pulmonary function and oxygenation improved.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0918-2918eISSN: 1349-7235DOI: 10.2169/internalmedicine.53.1728Titel-ID: cdi_proquest_miscellaneous_1554466032
- Format
- –
- Schlagworte
- Aged, Amyloidosis - complications, Amyloidosis - diagnostic imaging, Amyloidosis - drug therapy, Amyloidosis - pathology, Antineoplastic Combined Chemotherapy Protocols - therapeutic use, Biopsy, Needle, Boronic Acids - administration & dosage, Bortezomib, diffuse parenchymal pulmonary amyloidosis, Female, ground glass attenuation, Humans, Lung Diseases - complications, Lung Diseases - diagnostic imaging, Lung Diseases - drug therapy, Lung Diseases - pathology, multiple myeloma, Multiple Myeloma - complications, Multiple Myeloma - diagnostic imaging, Multiple Myeloma - pathology, Pyrazines - administration & dosage, Radiography, Treatment Outcome