Journal of bioscience and bioengineering, 2014-09, Vol.118 (3), p.341-343
2014
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Details
- Autor(en) / Beteiligte
- Titel
- Expression of a novel recombinant fusion protein BVN-Tβ4 and its effects on diabetic wound healing
- Ist Teil von
- Journal of bioscience and bioengineering, 2014-09, Vol.118 (3), p.341-343
- Ort / Verlag
- Amsterdam: Elsevier B.V
- Erscheinungsjahr
- 2014
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A recombinant fusion protein BVN-Tβ4 is successfully expressed in Escherichia coli, purified in the laboratory and applied onto the wounds of diabetic mice to investigate its effects on diabetic wound healing. Our results show that the recombinant protein BVN-Tβ4 can promote diabetic wound healing in the murine model.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1389-1723eISSN: 1347-4421DOI: 10.1016/j.jbiosc.2014.02.022Titel-ID: cdi_proquest_miscellaneous_1552370414
- Format
- –
- Schlagworte
- Amphibian Proteins - genetics, Amphibian Proteins - metabolism, Animals, Antimicrobial Cationic Peptides - genetics, Antimicrobial Cationic Peptides - metabolism, Base Sequence, Biological and medical sciences, Biotechnology, BVN-Tβ4, Diabetes Complications - chemically induced, Diabetes Complications - pathology, Diabetes Complications - therapy, Diabetes Mellitus, Experimental - chemically induced, Diabetes Mellitus, Experimental - pathology, Diabetes Mellitus, Experimental - therapy, Diabetic, Escherichia coli, Escherichia coli - genetics, Escherichia coli - metabolism, Fundamental and applied biological sciences. Psychology, Fusion protein, Gene Expression, Injections, Intralesional, Mice, Molecular Sequence Data, Ranidae, Recombinant Fusion Proteins - genetics, Recombinant Fusion Proteins - metabolism, Recombinant Fusion Proteins - therapeutic use, Skin Ulcer - pathology, Skin Ulcer - therapy, Streptozocin, Thymosin - genetics, Thymosin - metabolism, Wound healing, Wound Healing - drug effects