Methods (San Diego, Calif.), 2014-05, Vol.67 (2), p.116-122
2014
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Details
- Autor(en) / Beteiligte
- Titel
- A brief review of methods for terminal functionalization of DNA
- Ist Teil von
- Methods (San Diego, Calif.), 2014-05, Vol.67 (2), p.116-122
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 2014
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- •Methods for covalent terminal functionalization of DNA are introduced, mainly on the technical aspect.•The basic principle and important factors of reaction conditions for each method are described and discussed.•Further applications of these functionalized DNA are also introduced. The functionalized DNA has been widely developed and played a more and more important role in life science and material science during last decades. Therefore, methods to effectively endue DNA new functions by modifying DNA have been developed quickly. In this review, we will give an introduction in the methods for covalent terminal functionalization of DNA, including solid-phase functionalization and solution coupling functionalization, mainly on the technical aspect. The application of these functionalized DNA will be also introduced.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1046-2023eISSN: 1095-9130DOI: 10.1016/j.ymeth.2013.11.004Titel-ID: cdi_proquest_miscellaneous_1544010747
- Format
- –
- Schlagworte
- Amides - chemical synthesis, Amides - chemistry, Catalysis, Click Chemistry, Copper - chemistry, DNA, DNA - chemical synthesis, Nanostructures - chemistry, Phosphoric Acids - chemistry, Solid-phase functionalization, Solid-Phase Synthesis Techniques, Solution coupling functionalization, Solutions, Terminal functionalization