Details

Autor(en) / Beteiligte

• Sarkar, Avik R
• Heo, Cheol Ho
• Lee, Hyo Won
• Park, Kyung Hee
• Suh, Young Ho
• Kim, Hwan Myung

Titel

Red Emissive Two-Photon Probe for Real-Time Imaging of Mitochondria Trafficking

Ist Teil von

• Analytical chemistry (Washington), 2014-06, Vol.86 (12), p.5638-5641

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Mitochondria trafficking plays an essential role for supplying energy in the neuronal system. We report here a red emissive two-photon probe for mitochondria (CMT-red) that showed high selectivity and robust staining ability for mitochondria, high photostability under a two-photon microscopy imaging condition, and low cytotoxicity. This probe can be easily loaded into live cells and tissue and used for real-time, high resolution imaging of the mitochondria trafficking in primary cortical neurons as well as in rat hippocampal tissue.