Details

Autor(en) / Beteiligte

• Longuet, Romain
• Willot, Stephanie
• Giniès, Jean-Louis
• Pélatan, Cecile
• Breton, Estelle
• Segura, Jean-François
• Bridoux, Laure
• Le Henaff, Gaelle
• Cagnard, Benoit
• Jobert, Agathe
• Cardonna, Joël
• Grimal, Isabelle
• Balençon, Martine
• Darviot, Estelle
• Delaperrière, Nadège
• Caldari, Dominique
• Piloquet, Hugues
• Dabadie, Alain

Titel

Immunization status in children with inflammatory bowel disease

Ist Teil von

• European journal of pediatrics, 2014-05, Vol.173 (5), p.603-608

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Inflammatory bowel diseases have an increased risk of infections due to immunosuppressive therapies. To report the immunization status according to previous recommendations and the reasons explaining a delay, a questionnaire was filled in by the pediatric gastroenterologist, concerning outpatients, in six tertiary centers and five local hospitals, in a study, from May to November 2011. One hundred and sixty-five questionnaires were collected, of which 106 Crohn's diseases, 41 ulcerative colitis, and 17 indeterminate colitis. Sex ratio was 87:78 M/F. Median age was 14.4 years old (4.2–20.0). One hundred and nine patients (66 %) were receiving or had received an immunosuppressive therapy (azathioprine, infliximab, methotrexate, or prednisone). Vaccines were up to date according to the vaccine schedule of French recommendations in 24 % of cases and according to the recommendations for inflammatory bowel disease in 4 % of cases. Coverage by vaccine was the following: diphtheria–tetanus–poliomyelitis 87 %, hepatitis B 38 %, pneumococcus 32 %, and influenza 22 %. Immunization delay causes were as follows: absence of proposal 58 %, patient refusal 41 %, fear of side effects 33 %, and fear of disease activation 5 %. Therefore, immunization coverage is insufficient in children with inflammatory bowel disease, due to simple omission or to refusal. A collaboration with the attending physicians and a targeted information are necessary.