Details

Autor(en) / Beteiligte

• Tülümen, Erol, MD
• Giustetto, Carla, MD
• Wolpert, Christian, MD
• Maury, Philippe, MD
• Anttonen, Olli, MD
• Probst, Vincent, MD
• Blanc, Jean-Jacques, MD
• Sbragia, Pascal, MD
• Scrocco, Chiara, MD
• Rudic, Boris, MD
• Veltmann, Christian, MD
• Sun, Yaxun, MD
• Gaita, Fiorenzo, MD
• Antzelevitch, Charles, PhD, FHRS
• Borggrefe, Martin, MD, PhD
• Schimpf, Rainer, MD

Titel

PQ segment depression in patients with short QT syndrome: A novel marker for diagnosing short QT syndrome?

Ist Teil von

• Heart rhythm, 2014-06, Vol.11 (6), p.1024-1030

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2014

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Background Patients with short QT syndrome (SQTS) have an increased risk for atrial tachyarrhythmias, ventricular tachyarrhythmias, and/or sudden cardiac death. PQ segment depression (PQD) is related to atrial fibrillation and carries a poor prognosis in the setting of acute inferior myocardial infarction and is a well-defined electrocardiographic (ECG) marker of acute pericarditis. Objective To evaluate the prevalence of PQD in SQTS and to analyze the association with atrial arrhythmias. Methods Digitalized 12-lead ECGs of SQTS patients were evaluated for PQD in all leads and for QT intervals in leads II and V5 . PQD was defined as ≥0.05 mV (0.5 mm) depression from the isoelectric line. Results A total of 760 leads from 64 SQTS patients (mean age 36 ± 18 years; 48 [75%] men) were analyzed. PQD was seen in 265 (35%) leads from 52 (81%) patients and was more frequent in leads II, V3 , aVF, V4 , and I (n = 43 [67%], n = 30 [47%], n = 27 [42%], n = 25 [39%], and n = 25 [39%], respectively). Nine of 64 (14%) patients presented with atrial tachyarrhythmias, and all of them had PQD. Conclusion Fifty-two of 64 (81%) patients with SQTS reveal PQD. As PQD is rarely observed in healthy individuals, this ECG stigma may constitute a novel marker for SQTS in addition to a short QT interval.