Details

Autor(en) / Beteiligte

• Mizuno, Shugo
• Isaji, Shuji
• Tanemura, Akihiro
• Kishiwada, Masashi
• Murata, Yasuhiro
• Azumi, Yoshinori
• Kuriyama, Naohisa
• Usui, Masanobu
• Sakurai, Hiroyuki
• Tabata, Masami

Titel

Anterior Approach to the Superior Mesenteric Artery by Using Nerve Plexus Hanging Maneuver for Borderline Resectable Pancreatic Head Carcinoma

Ist Teil von

• Journal of gastrointestinal surgery, 2014-06, Vol.18 (6), p.1209-1215

Ort / Verlag

Boston: Springer US

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• To achieve R0 resection for pancreatic ductal adenocarcinoma (PDAC) of the pancreatic head, complete resection of the retropancreatic nerve plexus around the superior mesenteric artery (SMA) is thought to be required. Twenty-five patients with borderline resectable right-sided PDAC were divided into two groups after neoadjuvant chemoradiotherapy: those with portal vein (PV) invasion alone ( n  = 12), and those with invasion of both PV and SMA ( n  = 13). A tape for guidance was passed in a space ventral to the SMA and behind the pancreatic parenchyma, followed by resection of the pancreatic parenchyma with the splenic vein. Another tape was passed behind the nerve plexus lateral to the hepatic artery and the SMA ventral to the inferior vena cava and the nerve plexus was dissected, resulting in complete resection of the nerve plexus around the SMA. Pathological findings revealed that the rates of R0, R01 (a margin less than 1 mm) and R1 were 58.3 %, 41.7 % and 0 % in PV group, and 53.8 %, 30.8 % and 15.4 % in PV/A group, respectively. The median survival time was 23.3 and 22.8 months in PV and PV/A groups, respectively. The plexus hanging maneuver for PDAC of the pancreatic head achieved complete resection of the retropancreatic nerve plexus around the SMA, helping to secure a negative surgical margin.