Details

Autor(en) / Beteiligte

• Nomura, Satoshi
• Watanabe, Masanori
• Komine, Osamu
• Shioya, Takeshi
• Toyoda, Tetsutaka
• Bou, Hideki
• Shibuya, Tetsuo
• Suzuki, Hideyuki
• Uchida, Eiji

Titel

Serum total bilirubin elevation is a predictor of the clinicopathological severity of acute appendicitis

Ist Teil von

• Surgery today (Tokyo, Japan), 2014-06, Vol.44 (6), p.1104-1108

Ort / Verlag

Tokyo: Springer Japan

Erscheinungsjahr

2014

Link zum Volltext

Quelle

SpringerLink (Online service)

Beschreibungen/Notizen

• Purpose Elevation of the serum total bilirubin (STB) level not stemming from hepatic dysfunction or biliary obstruction may be seen in cases of acute appendicitis. This paper deals with the clinical significance of such elevations. Methods Data from 410 appendectomized patients classified into two groups (a high preoperative STB group and a normal preoperative STB group) were analyzed to reveal the significance of preoperative hyperbilirubinemia. We also examined whether the preoperative STB level might serve as a risk factor for gangrenous appendicitis by a multivariate analysis. Results Gangrenous appendicitis was more common in the high preoperative STB group ( p  < 0.001). The multivariate analysis revealed that an elevated preoperative STB level (odds ratio 1.7919) was a risk factor for gangrenous appendicitis. Conclusion In patients with an elevated preoperative STB level, it is very likely that the inflammation is severe and that the disease has progressed to a severe condition histopathologically; therefore, meticulous attention should be paid to the selection of the surgical procedure, as well as to the postoperative clinical course.