Details

Autor(en) / Beteiligte

• Cheng, Shih-Tsung, MD
• Wu, Yao-Kuang, MD
• Yang, Mei-Chen, MD
• Huang, Chun-Yao, MD
• Huang, Hui-Chuan, MSN
• Chu, Wen-Hua, MS
• Lan, Chou-Chin, MD, PhD

Titel

Pulmonary rehabilitation improves heart rate variability at peak exercise, exercise capacity and health-related quality of life in chronic obstructive pulmonary disease

Ist Teil von

• Heart & lung, 2014-05, Vol.43 (3), p.249-255

Ort / Verlag

United States: Mosby, Inc

Erscheinungsjahr

2014

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Objective Patients with chronic obstructive pulmonary disease (COPD) appear to have impaired cardiac autonomic modulation with depressed heart rate variability (HRV). Pulmonary rehabilitation (PR) is recommended as an integral part of the management. However, the effect of PR on HRV at peak exercise remains unclear. Methods Sixty-four patients with COPD participated in a 12-week, 2 sessions-per-week, hospital-based PR program. Baseline and post-PR status were evaluated by spirometry, HRV, health-related quality of life (HRQL, St. George's Respiratory Questionnaire, SGRQ), cardiopulmonary exercise test, respiratory muscle strength, and dyspnea Borg's scale. Results After PR, there were significant improvements in the time and frequency domains of HRV with increased standard deviation of the normal R–R intervals, difference between adjacent normal R–R intervals within a given time minus one, high-frequency and decreased low-frequency, as well as concurrent improvements in HRQL, exercise capacity, dyspnea score, and respiratory muscle strength (all p  < 0.05). Conclusions PR results in significant improvements in autonomic function, with concurrent improvements in HRQL and exercise capacity.