Details

Autor(en) / Beteiligte

• Williams, Thomas J
• Reay, Alan J
• Whitwood, Adrian C
• Fairlamb, Ian J S

Titel

A mild and selective Pd-mediated methodology for the synthesis of highly fluorescent 2-arylated tryptophans and tryptophan-containing peptides: a catalytic role for Pd(0) nanoparticles?

Ist Teil von

• Chemical communications (Cambridge, England), 2014-03, Vol.50 (23), p.3052-3054

Ort / Verlag

England

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• A Pd-mediated direct C-H bond functionalisation of tryptophan has been developed, both as a single amino acid residue and within peptides. Important mechanistic insight into this process has been gained by characterising a Pd catalytically competent nanoparticle phase which evolves during the early stages of reaction.