FEBS letters, 1987-11, Vol.224 (1), p.104-108
1987
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Details
- Autor(en) / Beteiligte
- Titel
- Induction and activation of tissue transglutaminase during programmed cell death
- Ist Teil von
- FEBS letters, 1987-11, Vol.224 (1), p.104-108
- Ort / Verlag
- Amsterdam: Elsevier B.V
- Erscheinungsjahr
- 1987
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- During the involution of lead nitrate-induced hyperplasia in rat liver a significant increase of transglutaminase activity, enzyme concentration, transglutaminase messenger RNA and protein-bound ε-(γ-glutamyl)lysine (product of transglutaminase action) coincided with programmed death (apoptosis) of hepatocytes. Immunohistochemical examination showed the appearance of transglutaminase in apoptotic hepatocytes. An increased transglutaminase level was also detected during glucocorticoid-induced apoptosis of rat thymocytes.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0014-5793eISSN: 1873-3468DOI: 10.1016/0014-5793(87)80430-1Titel-ID: cdi_proquest_miscellaneous_14997090
- Format
- –
- Schlagworte
- Ageing, cell death, Animals, Apoptosis, Biological and medical sciences, Cell physiology, Cell Survival, Enzyme Activation, Enzyme Induction, Fundamental and applied biological sciences. Psychology, Glucocorticoids - pharmacology, Hepatocyte, Hyperplasia, Lead - toxicity, Liver - drug effects, Liver - enzymology, Liver - pathology, Molecular and cellular biology, mRNA, Nitrates - toxicity, Rats, T-Lymphocytes - drug effects, T-Lymphocytes - enzymology, Thymocyte, Transglutaminase, Transglutaminases - metabolism, ε-(γ-Glutamyl)lysine