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Morphine three-dimensional T1 gadoxetate MR cholangiography of potential living related liver donors
Journal of magnetic resonance imaging, 2014-03, Vol.39 (3), p.584-589
Agrawal, Mukta D.
Mennitt, Kevin W.
Zhang, Honglei
Samstein, Benjamin
Kato, Tomoaki
Emond, Jean C.
Dutruel, Silvina P.
Thimmappa, Nanda Deepa
Prince, Martin R.
2014
Details
Autor(en) / Beteiligte
Agrawal, Mukta D.
Mennitt, Kevin W.
Zhang, Honglei
Samstein, Benjamin
Kato, Tomoaki
Emond, Jean C.
Dutruel, Silvina P.
Thimmappa, Nanda Deepa
Prince, Martin R.
Titel
Morphine three-dimensional T1 gadoxetate MR cholangiography of potential living related liver donors
Ist Teil von
Journal of magnetic resonance imaging, 2014-03, Vol.39 (3), p.584-589
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2014
Link zum Volltext
Quelle
Wiley Blackwell Single Titles
Beschreibungen/Notizen
Purpose To assess low‐dose morphine for distension and improved visualization of intrahepatic bile ducts on T1 MR cholangiography (MRC) in preoperative imaging of potential liver donors. Materials and Methods Sixty‐nine consecutive potential living related liver donors (mean age, 39 years; age range, 20 to 59 years) referred for pre‐transplant MRI evaluation were evaluated without (n = 30) or with (n = 39) intravenous morphine injection (0.04 mg/kg). Morphine was injected pre‐MRI while establishing intravenous access to allow ∼1 h for biliary distension before T1 MRC. Three radiologists reviewed intrahepatic biliary branch order visualization, common bile duct (CBD) diameter, and overall image quality. In 25 patients undergoing liver donation surgery, T1 MRC findings were correlated with intraoperative findings. This retrospective study was approved by the institutional review board. Results Biliary visualization was improved post‐morphine administration with biliary duct branch order visualization score of 3.2 and 3.3 at 45 and 60 min, respectively, compared with 2.7 without morphine (P < 0.002); CBD diameter measured 5.3 and 5.5 versus 4.1 mm (P < 0.005), and overall image quality score was 2.4 and 2.6 versus 1.8 (P < 0.0006). Operative notes confirmed T1 MRC findings in 6/11 donors without morphine and 14/14 donors with morphine. Conclusion Intravenous low‐dose morphine distends and improves visualization of bile ducts on T1 gadoxetate MRC. J. Magn. Reson. Imaging 2014;39:584–589. © 2013 Wiley Periodicals, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 1053-1807
eISSN: 1522-2586
DOI: 10.1002/jmri.24188
Titel-ID: cdi_proquest_miscellaneous_1499150429
Format
–
Schlagworte
Adult
,
Bile Ducts, Intrahepatic - drug effects
,
Chi-Square Distribution
,
Cholangiography - methods
,
Cohort Studies
,
Dose-Response Relationship, Drug
,
Family
,
Female
,
Gadolinium DTPA
,
gadoxetate
,
hepatic MRI
,
Humans
,
Image Processing, Computer-Assisted
,
Imaging, Three-Dimensional
,
Infusions, Intravenous
,
Liver Transplantation - methods
,
Living Donors
,
living related liver donor
,
Magnetic resonance imaging
,
Magnetic Resonance Imaging - methods
,
Male
,
Middle Aged
,
Morphine - administration & dosage
,
MR cholangiography
,
Preoperative Care - methods
,
Reference Values
,
Retrospective Studies
,
Statistics, Nonparametric
,
Young Adult
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