Details

Autor(en) / Beteiligte

• Santo, Hiroshi
• Nishiyama, Osamu
• Sano, Hiroyuki
• Kitaichi, Masanori
• Kume, Hiroaki
• Tohda, Yuji

Titel

Mediastinal Fibrosis and Positive Antineutrophil Cytoplasmic Antibodies: Coincidence or Common Etiology?

Ist Teil von

• Internal Medicine, 2014, Vol.53(3), pp.275-277

Ort / Verlag

Japan: The Japanese Society of Internal Medicine

Erscheinungsjahr

2014

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Retroperitoneal fibrosis (RPF) with positive antineutrophil cytoplasmic antibodies (ANCA) has been reported in several cases. We herein present the case of a 52-year-old woman who was diagnosed with mediastinal fibrosis (MF) on a thoracoscopic surgical biopsy. The patient had positive myeloperoxidase ANCA and thereafter developed crescentic glomerulonephritis, which was considered to be a form of ANCA-related nephritis. Both the MF and crescentic glomerulonephritis favorably responded to immunosuppressive therapy. These findings suggest a common pathogenesis of these disorders involving ANCA positivity, as reported in patients with RPF.