Details

Autor(en) / Beteiligte

• Xia, Ran
• Xie, Ming-Sheng
• Niu, Hong-Ying
• Qu, Gui-Rong
• Guo, Hai-Ming

Titel

Radical Route for the Alkylation of Purine Nucleosides at C6 via Minisci Reaction

Ist Teil von

• Organic letters, 2014-01, Vol.16 (2), p.444-447

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• A highly regioselective Minisci reaction with the decarboxylative alkylation of purine nucleosides under mild conditions was developed. With 5 mol % AgNO3 as a catalyst and (NH4)2S2O8 as an oxidant, a series of purine nucleosides including ribosyl, deoxyribosyl, arabinosyl purine nucleosides worked well with primary, secondary, and tertiary aliphatic carboxylic acids.