Details

Autor(en) / Beteiligte

• Conrad, Rachel
• Perez, Mia C N

Titel

Congenital granular cell epulis

Ist Teil von

• Archives of pathology & laboratory medicine (1976), 2014-01, Vol.138 (1), p.128-131

Ort / Verlag

United States: College of American Pathologists

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Congenital granular cell epulis is a rarely reported lesion of unknown histogenesis with a strong predilection for the maxillary alveolar ridge of newborn girls. Microscopically, it demonstrates nests of polygonal cells with granular cytoplasm, a prominent capillary network, and attenuated overlying squamous epithelium. The lesion lacks immunoreactivity for S-100, laminin, chromogranin, and most other markers except neuron-specific enolase and vimentin. Through careful observation of its unique clinical, histopathologic, and immunohistochemical features, this lesion can be distinguished from the more common adult granular cell tumor as well as other differential diagnoses.