Details

Autor(en) / Beteiligte

• Strollo, Patrick J
• Soose, Ryan J
• Maurer, Joachim T
• de Vries, Nico
• Cornelius, Jason
• Froymovich, Oleg
• Hanson, Ronald D
• Padhya, Tapan A
• Steward, David L
• Gillespie, M. Boyd
• Woodson, B. Tucker
• Van de Heyning, Paul H
• Goetting, Mark G
• Vanderveken, Oliver M
• Feldman, Neil
• Knaack, Lennart
• Strohl, Kingman P

Titel

Upper-Airway Stimulation for Obstructive Sleep Apnea

Ist Teil von

• The New England journal of medicine, 2014-01, Vol.370 (2), p.139-149

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2014

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• In this single-cohort study of patients with obstructive sleep apnea who could not adhere to treatment with continuous positive airway pressure, stimulation of the upper-airway muscles in synchrony with ventilatory efforts improved sleep quality. Obstructive sleep apnea is a common disorder, characterized by recurrent narrowing and closure of the upper airway accompanied by intermittent oxyhemoglobin desaturation and sympathetic activation. 1 Sequelae include excessive sleepiness and impaired quality of life. Moderate-to-severe obstructive sleep apnea, defined as an apnea–hypopnea index (AHI) score of 15 or more apnea or hypopnea events per hour, is an independent risk factor for insulin resistance, dyslipidemia, vascular disease, and death. 2 – 7 Treatment with continuous positive airway pressure (CPAP) with the use of a mask favorably modifies these adverse health consequences. 8 However, the general effectiveness of CPAP therapy is dependent on patient acceptance . . .