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Beschreibungen/Notizen
A literature review was conducted on adverse effects associated with administration of high oral doses of pyridoxine (vitamin B
6) to animals and man. The human data suggest that doses of pyridoxine greater than 500 mg/day for prolonged periods of time can result in sensory nerve damage. Doses less than 500 mg/day appear to be safe on the basis of literature reports where the compound was administered for periods ranging from 6 months to 6 years.