Details

Autor(en) / Beteiligte

• Alfaro, A. González
• Hernández, P. Campos
• Gómez, E. Gómez
• Garcia, J. Ruiz
• Carazo, J.L. Carazo
• López, F. Márquez
• Curado, F.J. Anglada
• Vallejo, M. Leva
• López, J.C. Regueiro
• Aljama, P
• Tapia, M.J. Requena

Titel

Variations in Initial Renal Transplant Function by Type of Organ Retrieval

Ist Teil von

• Transplantation proceedings, 2013-12, Vol.45 (10), p.3603-3605

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2013

Quelle

ScienceDirect

Beschreibungen/Notizen

• Abstract Background Numerous factors have been associated with early delay in kidney function and thence the graft survival. However, few data are derived from different types of donation: single or multiorgan. Our goal was to analyze the association of type of retrieval with the early function of the renal graft. Methods A retrospective analysis of transplantations performed in the Reina Sofia Hospital from January 2004 to June 2012 from local deceased donors was carried out. We performed a descriptive analysis of the variables and univariate and multivariate analyses with the use of logistic regression to determine the association of type of retrieval (kidney-only [KO], kidney-liver [KL], and multiorgan [MO]) with delayed graft function (DGF) and early graft failure (EGF). Results We analyzed 287 kidney transplantations from 182 deceased donors, of which 25 (13.7%) were KO, 80 (43.9%) KL, and 77 (42.3%) MO. DGF was higher in MO retrievals compared with KL and KO (25.8% vs 24% vs 20.5%), though without reaching significance ( P  = .81). EGF at 3 months was 17.6% in KO compared with 10.5% in KL and 5.3% in MO ( P  = .2). Regarding DGF, in the multivariate analysis, donor age ( P  = .049) and donor sex ( P  = .029) appeared to be related to DGF. There were no differences by type of retrieval. Multivariate logistic regression analysis established a significant relationship between KO retrieval and EGF at 3 months ( P  = .005) compared with MO. Conclusions Early graft function at 3 months decreases when the allograft is from KO retrievals compared with MO, probably related to the more unfavorable characteristics of these donors and their corresponding recipients.