Details

Autor(en) / Beteiligte

• Eom, B.W
• Joo, J
• Kim, Y.W
• Bae, J.M
• Park, K.B
• Lee, J.H
• Ryu, K.W
• Kook, M.C

Titel

Role of bursectomy for advanced gastric cancer: Result of a case–control study from a large volume hospital

Ist Teil von

• European journal of surgical oncology, 2013-12, Vol.39 (12), p.1407-1414

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2013

Quelle

ScienceDirect

Beschreibungen/Notizen

• Abstract Aims According to the recent Japanese Gastric Cancer Association's gastric cancer treatment guidelines, bursectomy is recommended for tumors penetrating the serosa of the posterior gastric wall. However, there is still little data to show whether bursectomy improves patient survival. The aim of this study is to evaluate the efficacy of bursectomy for subserosa or serosa-positive gastric cancer in terms of overall survival. Method From April 2001 to December 2006, 470 patients underwent curative resection for macroscopically subserosa or serosa-positive gastric cancer. These patients were grouped according to whether bursectomy was performed or not (bursectomy+/bursectomy−). Clinicopathological characteristics and incidence of complications were compared between the groups. The overall survival rates were analyzed using a Cox proportional hazards model. Results There was no significant difference in morbidity and mortality between the bursectomy+ and bursectomy− groups. In the multivariable analysis for overall survival, bursectomy was not a significant independent factor ( p  = 0.978). In the subgroup analysis for clinical and pathological stage III and IV, and tumors penetrating the serosa of the posterior gastric wall, bursectomy did not have significant effect on overall survival as well ( p  = 0.582, 0.453, and 0.532, respectively). In the propensity score-matched patients, bursectomy still showed no significant effect on overall survival ( p  = 0.804). Conclusions Bursectomy is unlikely to improve overall survival in patients with macroscopically subserosa or serosa-positive gastric cancer.