Details

Autor(en) / Beteiligte

• Leon-Ferre, Roberto A., MD
• Koch, Benjamin, MD
• Rosenstein, Lori J., MD

Titel

A B-wildering Case of Paraplegia: Cobalamin Deficiency

Ist Teil von

• The American journal of medicine, 2013-12, Vol.126 (12), p.1045-1047

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• Leon-Ferre et al present the case of a 36-year-old Caucasian man, who was presented spastic paraplegia, decreased lower-extremity sensation, and sphincter incontinence. The patient had a cobalamin--or B12--deficiency caused by impaired B12 absorption secondary to chronic atrophic gastritis. Cobalamin is a cofactor required during DNA synthesis in proliferating cells. He was started on a regimen of intramuscular vitamin B12, which quickly produced a reticulocyte response. At a 3-month follow-up visit, the patient's blood counts and red blood cell indices had normalized. He was still wheelchair-bound but was able to move his toes.