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Spinal bone defects in neurofibromatosis type I with dural ectasia: stress fractures or dysplastic? A case series
Ist Teil von
European radiology, 2013-12, Vol.23 (12), p.3418-3421
Ort / Verlag
Berlin/Heidelberg: Springer Berlin Heidelberg
Erscheinungsjahr
2013
Quelle
MEDLINE
Beschreibungen/Notizen
Objectives
Neurofibromatosis type I (NF1) is a multisystem neurocutaneous disorder with varied musculoskeletal manifestations. Dural ectasia is a known association, whilst pedicular anomalies have been described, although not as frequently as other skeletal manifestations. However, reports of pedicular and other spinal clefts or fractures in combination with dural ectasia in NF1 are scarce. We aimed to identify osseous defects in the posterior elements of NF1 patients with dural ectasia.
Methods
Images of patients with NF1 and back pain were reviewed for osseous defects in the posterior elements.
Results
Four patients were identified with NF1, back pain, dural ectasia and bone defects. The imaging appearances of the defects are illustrated.
Conclusions
Defects in the spinal posterior elements of patients with NF1, back pain and dural ectasia may be dysplastic, stress fractures or, most probably, multifactorial in origin. Computed tomography demonstrates these defects most clearly.
Key Points
• Dural ectasia with posterior element dysplasia is common in neurofibromatosis.
• Pedicle defects, which may be stress fractures, occur in NF1.
• Posterior element defects should be sought in NF1 patients with back pain.