Details

Autor(en) / Beteiligte

• Khoo Bao, Jenn Nee
• Ogunwale, Bamikole
• Huson, Susan M.
• Ealing, John
• Whitehouse, Richard W.

Titel

Spinal bone defects in neurofibromatosis type I with dural ectasia: stress fractures or dysplastic? A case series

Ist Teil von

• European radiology, 2013-12, Vol.23 (12), p.3418-3421

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• Objectives Neurofibromatosis type I (NF1) is a multisystem neurocutaneous disorder with varied musculoskeletal manifestations. Dural ectasia is a known association, whilst pedicular anomalies have been described, although not as frequently as other skeletal manifestations. However, reports of pedicular and other spinal clefts or fractures in combination with dural ectasia in NF1 are scarce. We aimed to identify osseous defects in the posterior elements of NF1 patients with dural ectasia. Methods Images of patients with NF1 and back pain were reviewed for osseous defects in the posterior elements. Results Four patients were identified with NF1, back pain, dural ectasia and bone defects. The imaging appearances of the defects are illustrated. Conclusions Defects in the spinal posterior elements of patients with NF1, back pain and dural ectasia may be dysplastic, stress fractures or, most probably, multifactorial in origin. Computed tomography demonstrates these defects most clearly. Key Points • Dural ectasia with posterior element dysplasia is common in neurofibromatosis. • Pedicle defects, which may be stress fractures, occur in NF1. • Posterior element defects should be sought in NF1 patients with back pain.