Details

Autor(en) / Beteiligte

• Sewald, N

Titel

Stereoselective synthesis ofβ-amino acids via conjugate addition of nitrogen nucleophiles toα,β-unsaturated esters - Recent advances

Ist Teil von

• Amino acids, 1996-09, Vol.11 (3-4), p.397-408

Ort / Verlag

Austria

Erscheinungsjahr

1996

Quelle

Springer journals

Beschreibungen/Notizen

• The latest results concerning the asymmetric synthesis ofβ-amino acids are reviewed, focussing on methodology involving 1,4-addition of nitrogen nucleophiles toα,β-unsaturated esters. Approaches using both homochiral auxiliaries bound to the enoate and homochiral ammonia equivalents are included as well as alkylations and aldol reactions of enolates derived from homochiralβ-amino acids.