Details

Autor(en) / Beteiligte

• Jiménez Caballero, Pedro Enrique, MD
• López Espuela, Fidel, BP, RN
• Portilla Cuenca, Juan Carlos, MD
• Ramírez Moreno, José María, MD
• Pedrera Zamorano, Juan Diego, PhD, MD
• Casado Naranjo, Ignacio, MD

Titel

Charlson Comorbidity Index in Ischemic Stroke and Intracerebral Hemorrhage as Predictor of Mortality and Functional Outcome after 6 Months

Ist Teil von

• Journal of stroke and cerebrovascular diseases, 2013-10, Vol.22 (7), p.e214-e218

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• Background The Charlson Comorbidity Index (CCI) is commonly used in outcome and mortality studies. Our aim was to investigate the association between CCI score and the functional outcome and mortality 6 months after ischemic stroke (IS) or intracerebral hemorrhage. Methods This was a prospective observational cohort of patients with spontaneous intracerebral hemorrhage and IS admitted to the stroke unit during 18 months. The modified Rankin scale (mRS) score was obtained for subjects 6 months after event. The CCI score was dichotomized (low comorbidity 0 or 1 versus high ≥2) for analysis. The mRS score was also dichotomized (good outcome, mRS score 0 or 1 versus poor outcome, mRS score ≥2). Results In all, 175 patients were enrolled in the study. Logistic regression showed that those with a high CCI score (≥2) had 37.3% increased odds of having a poor outcome (≥2) at 6 months and 68.4% greater odds of death at 6 months. Conclusions Comorbid medical conditions independently influence outcome after IS or intracerebral hemorrhage.