Vaccine, 2013-04, Vol.31 (18), p.2253-2259
2013
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- Autor(en) / Beteiligte
- Titel
- Efficacy, safety and immunogenicity of a human rotavirus vaccine (RIX4414) in Hong Kong children up to three years of age: A randomized, controlled trial
- Ist Teil von
- Vaccine, 2013-04, Vol.31 (18), p.2253-2259
- Ort / Verlag
- Kidlington: Elsevier Ltd
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Efficacy, immunogenicity and safety of RIX4414 vaccine in Hong Kong infants. • Randomized double-blind, placebo-controlled study of 3025 infants. • Vaccine efficacy against severe RVGE was 95.6% (<2 years) and 96.1% (<3 years). • No safety concern was identified.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0264-410XeISSN: 1873-2518DOI: 10.1016/j.vaccine.2013.03.001Titel-ID: cdi_proquest_miscellaneous_1443367233
- Format
- –
- Schlagworte
- Administration, Oral, Age, Allergy and Immunology, Antibodies, Viral - blood, Antibodies, Viral - immunology, Applied microbiology, Biological and medical sciences, Child, Preschool, children, Children & youth, Diarrhea, Double-Blind Method, Efficacy, enzyme-linked immunosorbent assay, Fundamental and applied biological sciences. Psychology, Gastroenteritis, Gastroenteritis - immunology, Gastroenteritis - prevention & control, Gastroenteritis - virology, Hong Kong, Human rotavirus, Humans, immune response, Immunization, Immunization Schedule, immunoglobulin A, Immunoglobulin A - blood, Immunoglobulin A - immunology, Infant, infants, Intussusception, Intussusception - chemically induced, Microbiology, Miscellaneous, Rotavirus, Rotavirus Infections - immunology, Rotavirus Infections - prevention & control, Rotavirus Vaccines - administration & dosage, Rotavirus Vaccines - adverse effects, Rotavirus Vaccines - therapeutic use, Safety, seroconversion, Vaccines, Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects), Virology