UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 10 von 177
Datensatz exportieren als...
BibTeX
Curcumin, a component of turmeric: From farm to pharmacy
BioFactors (Oxford), 2013-01, Vol.39 (1), p.2-13
Gupta, Subash C.
Kismali, Gorkem
Aggarwal, Bharat B.
2013
Details
Autor(en) / Beteiligte
Gupta, Subash C.
Kismali, Gorkem
Aggarwal, Bharat B.
Titel
Curcumin, a component of turmeric: From farm to pharmacy
Ist Teil von
BioFactors (Oxford), 2013-01, Vol.39 (1), p.2-13
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2013
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Curcumin, an active polyphenol of the golden spice turmeric, is a highly pleiotropic molecule with the potential to modulate the biological activity of a number of signaling molecules. Traditionally, this polyphenol has been used in Asian countries to treat such human ailments as acne, psoriasis, dermatitis, and rash. Recent studies have indicated that curcumin can target newly identified signaling pathways including those associated with microRNA, cancer stem cells, and autophagy. Extensive research from preclinical and clinical studies has delineated the molecular basis for the pharmaceutical uses of this polyphenol against cancer, pulmonary diseases, neurological diseases, liver diseases, metabolic diseases, autoimmune diseases, cardiovascular diseases, and numerous other chronic diseases. Multiple studies have indicated the safety and efficacy of curcumin in numerous animals including rodents, monkeys, horses, rabbits, and cats and have provided a solid basis for evaluating its safety and efficacy in humans. To date, more than 65 human clinical trials of curcumin, which included more than 1000 patients, have been completed, and as many as 35 clinical trials are underway. Curcumin is now used as a supplement in several countries including the United States, India, Japan, Korea, Thailand, China, Turkey, South Africa, Nepal, and Pakistan. In this review, we provide evidence for the pharmaceutical uses of curcumin for various diseases. © 2013 BioFactors, 39(1):2–13, 2013
Sprache
Englisch
Identifikatoren
ISSN: 0951-6433
eISSN: 1872-8081
DOI: 10.1002/biof.1079
Titel-ID: cdi_proquest_miscellaneous_1434013085
Format
–
Schlagworte
Animals
,
Antineoplastic Agents - pharmacology
,
Antineoplastic Agents - therapeutic use
,
autophagy
,
Autophagy - drug effects
,
cancer stem cells
,
Clinical Trials as Topic
,
Curcuma - chemistry
,
Curcuma longa
,
curcumin
,
Curcumin - pharmacology
,
Curcumin - therapeutic use
,
Drug Evaluation, Preclinical
,
Gene Expression Regulation - drug effects
,
Humans
,
Medicine, Traditional
,
microRNA
,
MicroRNAs - genetics
,
MicroRNAs - metabolism
,
Neoplasms - drug therapy
,
Neoplastic Stem Cells - drug effects
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX