Bulletin of experimental biology and medicine, 2000-09, Vol.130 (3), p.849-851
2000
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Behavioral peculiarities and reactions of brain dopaminergic systems in rats with different resistance to acute hypobaric hypoxia
- Ist Teil von
- Bulletin of experimental biology and medicine, 2000-09, Vol.130 (3), p.849-851
- Ort / Verlag
- New York: Springer Nature B.V
- Erscheinungsjahr
- 2000
- Quelle
- SpringerLINK Contemporary (Konsortium Baden-Württemberg)
- Beschreibungen/Notizen
- Locomotor activity in the open field test did not correlate with rat resistance to acute hypobaric hypoxia; there was a correlation between this resistance and rat behavior during acute stress. Immobility was characteristic of rats with low and particularly medium resistance to hypoxia; this reaction can be abolished by antidepressants. By contrast, highly resistant rats were mainly hyperactive. The resistance to hypoxia was associated with extreme parameters of dopaminergic neuron functioning. In low-resistant rats locomotor stereotypia was maximal, while perioral stereotypia was the minimal; highly resistant rats were characterized by an opposite pattern, and medium-resistant rats occupied an intermediate position.[PUBLICATION ABSTRACT]