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Best ethical practices for clinicians and laboratories in the provision of noninvasive prenatal testing
Prenatal diagnosis, 2013-07, Vol.33 (7), p.656-661
Allyse, M. A.
Sayres, L. C.
Havard, M.
King, J. S.
Greely, H. T.
Hudgins, L.
Taylor, J.
Norton, M. E.
Cho, M. K.
Magnus, D.
Ormond, K. E.
2013
Details
Autor(en) / Beteiligte
Allyse, M. A.
Sayres, L. C.
Havard, M.
King, J. S.
Greely, H. T.
Hudgins, L.
Taylor, J.
Norton, M. E.
Cho, M. K.
Magnus, D.
Ormond, K. E.
Titel
Best ethical practices for clinicians and laboratories in the provision of noninvasive prenatal testing
Ist Teil von
Prenatal diagnosis, 2013-07, Vol.33 (7), p.656-661
Ort / Verlag
England: Blackwell Publishing Ltd
Erscheinungsjahr
2013
Link zum Volltext
Quelle
Wiley Blackwell Single Titles
Beschreibungen/Notizen
ABSTRACT Objective The goal of this study is to provide an ethical framework for clinicians and companies providing noninvasive prenatal testing using cell‐free fetal DNA or whole fetal cells. Method In collaboration with a National Institutes of Health‐supported research ethics consultation committee together with feedback from an interdisciplinary group of clinicians, members of industry, legal experts, and genetic counselors, we developed a set of best practices for the provision of noninvasive prenatal genetic testing. Results Principal recommendations include the amendment of current informed consent procedures to include attention to the noninvasive nature of new testing and the potential for a broader range of results earlier in the pregnancy. We strongly recommend that tests should only be provided through licensed medical providers and not directly to consumers. Conclusion Prenatal tests, including new methods using cell‐free fetal DNA, are not currently regulated by government agencies, and limited professional guidance is available. In the absence of regulation, companies and clinicians should cooperate to adopt responsible best ethical practices in the provision of these tests. © 2013 John Wiley & Sons, Ltd. What's already known about this topic? Noninvasive prenatal genetic testing using cell‐free fetal DNA or whole fetal cells has ethical implications pertaining to its commercial and clinical provision. What does this study add? This paper provides a set of best ethical practices for clinicians and companies providing noninvasive prenatal genetic testing.
Sprache
Englisch
Identifikatoren
ISSN: 0197-3851
eISSN: 1097-0223
DOI: 10.1002/pd.4144
Titel-ID: cdi_proquest_miscellaneous_1398425014
Format
–
Schlagworte
DNA - blood
,
Female
,
Fetus - chemistry
,
Fetus - cytology
,
Genetic Testing - ethics
,
Genetic Testing - methods
,
Health Personnel - ethics
,
Humans
,
Informed Consent
,
Laboratories - ethics
,
National Institutes of Health (U.S.)
,
Practice Guidelines as Topic
,
Pregnancy
,
Prenatal Diagnosis - ethics
,
Prenatal Diagnosis - methods
,
United States
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