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Is it right to look for anti-cancer drugs amongst compounds having antioxidant effect?
Ist Teil von
Daru, 2012-10, Vol.20 (10), p.1-1
Ort / Verlag
New York: Springer Nature B.V
Erscheinungsjahr
2012
Link zum Volltext
Quelle
Electronic Journals Library
Beschreibungen/Notizen
In recent years, there has been a mounting interest on the use of natural products with antioxidant effect in the management of cancer. However, although the beneficial role of antioxidants in cancer prevention has been well described, it is still doubtful whether or not antioxidants are effective in the treatment of cancer. Theoretically, antioxidants scavenge superoxide anion radical and thus deplete the supply of intracellular hydrogen peroxide which may deteriorate cancer conditions. On the other hand, they scavenge hydroxyl radicals which have beneficial effects. Therefore, the authors believe that use of antioxidants during chemotherapy of cancer could diminish benefits of chemotherapy or radiation to the patient by scavenging free radicals.