Cancer letters, 2013-07, Vol.335 (1), p.81-92
2013
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Details
- Autor(en) / Beteiligte
- Titel
- Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres
- Ist Teil von
- Cancer letters, 2013-07, Vol.335 (1), p.81-92
- Ort / Verlag
- Ireland: Elsevier Ireland Ltd
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • CXCL8 transcripts are highly expressed in the NPC tissues. • MIF/CXCL8/CXCR2 signaling is involved in the in vitro growth of EBV-positive NPC tumor spheres. • Growth promoting function of CXCL8 could be inhibited through the pathway inhibition.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0304-3835eISSN: 1872-7980DOI: 10.1016/j.canlet.2013.01.052Titel-ID: cdi_proquest_miscellaneous_1356388566
- Format
- –
- Schlagworte
- Angiogenesis, Antibiotics, Biomarkers, Biopsy, Breast cancer, Carcinoma - metabolism, Carcinoma - pathology, Cell Line, Tumor, Cell Movement, Cell Proliferation, Chemokines, Chromones - pharmacology, CXCL8, CXCR2, Gene Expression, Gene Knockdown Techniques, Hematology, Oncology and Palliative Medicine, Humans, Interleukin-8 - antagonists & inhibitors, Interleukin-8 - genetics, Interleukin-8 - metabolism, Intramolecular Oxidoreductases - genetics, Intramolecular Oxidoreductases - metabolism, Macrophage Migration-Inhibitory Factors - genetics, Macrophage Migration-Inhibitory Factors - metabolism, Metastasis, MIF, Morpholines - pharmacology, Nasopharyngeal carcinoma, Nasopharyngeal Neoplasms - metabolism, Nasopharyngeal Neoplasms - pathology, NF-kappa B - genetics, NF-kappa B - metabolism, Phenylurea Compounds - pharmacology, Phosphatidylinositol 3-Kinases - antagonists & inhibitors, Phosphatidylinositol 3-Kinases - metabolism, Receptors, Interleukin-8B - antagonists & inhibitors, Receptors, Interleukin-8B - genetics, Receptors, Interleukin-8B - metabolism, RNA, Small Interfering - genetics, Signal Transduction, Snail Family Transcription Factors, Spheres, Spheroids, Cellular - metabolism, Spheroids, Cellular - pathology, Transcription Factors - genetics, Transcription Factors - metabolism, Tumour spheres