Details

Autor(en) / Beteiligte

• Blitzblau, Rachel C
• Horton, Janet K

Titel

Radiotherapy after mastectomy

Ist Teil von

• Surgical oncology clinics of North America, 2013-07, Vol.22 (3), p.563-577

Ort / Verlag

United States

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• Classic randomized trials documented the benefit of postmastectomy radiotherapy in women with node-positive or locally advanced breast cancer. Modern advances in surgical therapy, systemic therapy, and radiotherapy, however, along with an improved understanding of cancer biology, have called into question previously assumed recurrence risks and treatment benefits. This article explores the impact of tumor biology and genomic medicine on utilization of postmastectomy radiotherapy and how treatment decision making is moving beyond TNM-based predictors.