Details

Autor(en) / Beteiligte

• Bourbon, Pauline
• Peng, Qian
• Ferraudi, Guillermo
• Stauffacher, Cynthia
• Wiest, Olaf
• Helquist, Paul

Titel

Synthesis and photochemical behavior of coumarin-caged cholesterol

Ist Teil von

• Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.2162-2165

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• The syntheses of three coumarin-caged cholesterols are reported that contain the 6-diethylaminocoumarin (DEACM), 6-bromo-7-hydroxycoumarin (BHC) and 6-bromo-7-methoxycoumarin (BMCM) photocleavable groups. Upon photolysis, the best caged derivative was found to be BHC-cholesterol whose quantum yield was determined to be 0.032 at 350nm.