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Successful Treatment of Serial Opportunistic Infections Including Disseminated Nocardiosis and Cryptococcal Meningitis in a Patient with ANCA-associated Vasculitis
Ist Teil von
Internal Medicine, 2012, Vol.51(21), pp.3051-3056
Ort / Verlag
Japan: The Japanese Society of Internal Medicine
Erscheinungsjahr
2012
Quelle
MEDLINE
Beschreibungen/Notizen
We herein present a case of serial opportunistic infections that included disseminated nocardiosis and cryptococcal meningitis in a 67-year-old man who was diagnosed with ANCA-associated vasculitis and treated with corticosteroids. Upon admission, the initial manifestations of the disease included subcutaneous tumors and multiple lesions in the brain and lungs. Nocardia farcinica was identified in a culture of the aspirated pus. The patient was successfully treated for disseminated nocardiosis with antibiotics. However, three months after discharge, he was hospitalized with complaints of nuchal pain. Cryptococcus neoformans was identified on a culture of the cerebrospinal fluid. Anti-fungal treatment resulted in the remission of cryptococcal meningitis.