Details

Autor(en) / Beteiligte

• Young, Duncan
• Lamb, Sarah E
• Shah, Sanjoy
• MacKenzie, Iain
• Tunnicliffe, William
• Lall, Ranjit
• Rowan, Kathy
• Cuthbertson, Brian H

Titel

High-Frequency Oscillation for Acute Respiratory Distress Syndrome

Ist Teil von

• The New England journal of medicine, 2013-02, Vol.368 (9), p.806-813

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• High-frequency oscillatory ventilation has been advocated for hypoxemia accompanying the acute respiratory distress syndrome. In this trial comparing HFOV with conventional ventilation, HFOV had no significant effect on 30-day mortality. The acute respiratory distress syndrome (ARDS) is a severe, diffuse inflammatory lung condition caused by a range of acute illnesses. Mortality in affected patients is high, 1 and survivors may have functional limitations for years. 2 , 3 Although mechanical ventilation can initially be lifesaving in patients with ARDS, it can also further injure the patients' lungs and contribute to death. 4 High-frequency oscillatory ventilation (HFOV) was first used experimentally in the 1970s to minimize the hemodynamic effects of mechanical ventilation. 5 Patients' lungs are held inflated to maintain oxygenation, and carbon dioxide is cleared by small volumes of gas moved in and out of . . .