Cancer letters, 2013-04, Vol.330 (2), p.123-129
2013
Details
- Autor(en) / Beteiligte
- Titel
- Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma
- Ist Teil von
- Cancer letters, 2013-04, Vol.330 (2), p.123-129
- Ort / Verlag
- Ireland: Elsevier Ireland Ltd
- Erscheinungsjahr
- 2013
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights ► HORMAD1 is a cancer/testis antigen expressed exclusively in germ cells during normal development. ► HORMAD1 is expressed in a substantial portion of human epithelial ovarian cancers. ► HORMAD1 down-regulation affected tumor growth in mouse models of human ovarian cancer.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0304-3835eISSN: 1872-7980DOI: 10.1016/j.canlet.2012.07.001Titel-ID: cdi_proquest_miscellaneous_1284290460
- Format
- –
- Schlagworte
- Angiogenesis, animal ovaries, Animals, Antigens, Apoptosis, Cancer therapies, carcinoma, Carcinoma, Ovarian Epithelial, Cell Cycle Proteins - antagonists & inhibitors, Cell Cycle Proteins - genetics, Cell Cycle Proteins - physiology, Cell Line, Tumor, Chemotherapy, cisplatin, Female, Gene expression, gene silencing, Grants, Hematology, Oncology and Palliative Medicine, HORMAD1, Humans, Kinases, Laboratory animals, Medical research, Mice, migratory behavior, Mortality, Neoplasm Invasiveness, Neoplasms, Glandular and Epithelial - genetics, Neoplasms, Glandular and Epithelial - metabolism, Neoplasms, Glandular and Epithelial - pathology, Ovarian cancer, ovarian neoplasms, Ovarian Neoplasms - genetics, Ovarian Neoplasms - metabolism, Ovarian Neoplasms - pathology, Proteins, RNA, Messenger - analysis, RNA, Small Interfering - genetics, Rodents, Tumor Microenvironment, Tumors, Vascular Endothelial Growth Factor A - analysis, Vascular Endothelial Growth Factor A - genetics, Vascular Endothelial Growth Factor A - metabolism, VEGF, Xenograft