Details

Autor(en) / Beteiligte

• Oliveros, A.
• Guiseppi-Elie, A.
• Jaroszeski, M.
• Saddow, S. E.

Titel

Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI)

Ist Teil von

• 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012, Vol.2012, p.1643-1646

Ort / Verlag

United States: IEEE

Erscheinungsjahr

2012

Quelle

IEL

Beschreibungen/Notizen

• Silicon Carbide (SiC), has been shown to be a bio- and hema-compatible substrate that could potentially be used in biosensor applications. The development of a viable biorecognition interface using SiC as the substrate material for bio-detection is described. Surface modification with 3-aminopropyltriethoxysilane (APTES) and immobilization via covalent conjugation of antimyoglobin (anti-Myo) on the modified surfaces is achieved, which are initial steps for immunosensing based devices. Successful formation of APTES layers and antibody immobilization were identified with surface water contact angle (SWCA), X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM).