Details

Autor(en) / Beteiligte

• Hu, Feng
• Yan, Jianwei
• Cheng, Ming
• Hu, Youhong

Titel

Gold-catalyzed Reactions of 3-Alkynyloxireno[2, 3-b]chromenones to Form 3(2H)-Furanones via a Domino Pathway

Ist Teil von

• Chemistry, an Asian journal, 2013-02, Vol.8 (2), p.482-487

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2013

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• 3(2H)‐Furanones are efficiently generated from 3‐alkynyl oxireno[2,3‐b]chromenones by an Au/DDQ‐catalyzed domino reaction through a pathway composed of cyclization, CC cleavage, nucleophilic addition, oxidation, and nucleophilic addition. It was found that stoichiometric AuCl3 or catalytic Au with stoichiometric DDQ can oxidize the benzylic sp3 CH bond to facilitate nucleophilic addition. Domino′s to deliver 3(2H)‐furanones: An Au/DDQ‐catalyzed domino reaction through a pathway comprising cyclization, CC cleavage, nucleophilic addition, oxidation, and nucleophilic addition is presented.